发明名称 |
A NOVEL NPG-1 GENE THAT IS DIFFERENTIALLY EXPRESSED IN PROSTATE TUMORS |
摘要 |
The invention provides isolated nucleic acid molecules, designated NPG-1 nucleic acid molecules, which encode polypeptides involved in the modulation of a response in a tumor cell. The invention also provides antisense nucleic acid molecules, expression vectors containing NPG-1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which an NPG-1 gene has been introduced or disrupted. The invention still further provides isolated NPG-1 polypeptides, fusion polypeptides, antigenic peptides, and anti-NPG-1 antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
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申请公布号 |
WO9941412(A1) |
申请公布日期 |
1999.08.19 |
申请号 |
WO1999US03029 |
申请日期 |
1999.02.11 |
申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER, INC.;SYTKOWSKI, ARTHUR;YANG, MEIHENG |
发明人 |
SYTKOWSKI, ARTHUR;YANG, MEIHENG |
分类号 |
A61K38/00;A61K48/00;C07K14/705;C12N15/10;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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