| 发明名称 |
CYCLIC DIPEPTIDES AND AZETIDINONE COMPOUNDS AND THEIR USE IN TREATING CNS INJURY AND NEURODEGENERATIVE DISORDERS |
| 摘要 |
The present invention provides 4-substituted-2-azetidinone compounds, bicyclic 2-5-diketopiperazine compounds, and pharmaceutical compositions thereof that are potent, safe and effective neuroprotective agents. Due to their strong central nervous system (CNS) activity, the compounds can be used to enhance memory and to treat a variety of neurological disorders. The compounds are particularly useful for treating neurological disorders caused by, or associated with, CNS trauma.
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| 申请公布号 |
WO9940931(A1) |
申请公布日期 |
1999.08.19 |
| 申请号 |
WO1999US03147 |
申请日期 |
1999.02.10 |
| 申请人 |
GEORGETOWN UNIVERSITY |
发明人 |
KOZIKOWSKI, ALAN, P.;FADEN, ALAN, I.;ARALDI, GIAN, LUCA |
| 分类号 |
A61K31/4985;A61K38/00;A61P25/00;A61P25/28;A61P43/00;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D471/04;C07D487/04;C07K5/06;C07K5/097;(IPC1-7):A61K38/05;A61K31/495;C07D241/04 |
主分类号 |
A61K31/4985 |
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