Processes for the production of anti-inflammatory steroids

摘要

Disclosed are processes for preparing the 22R and 22S epimers of the compound The processes involve acetalization, transacetalization, hydrolysis (of an ester) or hydrogenation (of a diene) of an appropriate starting material. Also disclosed are pharmaceutical compositions comprising the compounds produced by the processes and methods of treatment of inflammatory and allergic conditions employing the compounds.