发明名称 CHELATED 8-HYDROXYQUINOLINE FOR THE TREATMENT OF EPITHELIAL LESIONS
摘要 Oxinates including 8-hydroxyquinoline and a heavy metal are topically applied to epidermal lesions for therapeutic effect. The therapeutic composition demonstrates selective toxicity with a therapeutic index of one-hundred percent on human lung cancer, breat cancer, melanoma, venereal warts, male veruoca warts, lesions produced by human papilloma virus, basal cell carcinoma, solarkeratosis, and Kaposi's sarcoma. In veterinary applications where dogs, cats, and horses are the patients, the composition shows a one-hundred percent therapeutic index with selective toxicity against eye cancer, sarcoids, sarcoma, malignant melanoma, rectal adenoma, histiocytoma, and sebaceous adenoma.
申请公布号 WO9939721(A1) 申请公布日期 1999.08.12
申请号 WO1999US02817 申请日期 1999.02.10
申请人 DERMEX PHARMACEUTICALS, LLC;JORDAN, RUSSEL, T.;HANSON, CARL, C.;POTESTIO, FRANK, S. 发明人 JORDAN, RUSSEL, T.;HANSON, CARL, C.;POTESTIO, FRANK, S.
分类号 A61K31/47;A61K33/24;A61K33/26;A61K33/30;A61K33/32;A61K33/34;A61K45/06;(IPC1-7):A61K33/00 主分类号 A61K31/47
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