| 发明名称 |
Recombinant human interleukin-1 alpha |
| 摘要 |
The invention relates to the cloning of the human IL-1 gene, its engineering into suitable expression vectors, transformation of host organisms with such expression vectors and production of biologically active recombinant human IL-1 by culture of such transformed cells. Additionally, the invention relates to the isolation and use of the resulting recombinant human IL-1 polypeptides.
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| 申请公布号 |
US5936066(A) |
申请公布日期 |
1999.08.10 |
| 申请号 |
US19940259927 |
申请日期 |
1994.06.15 |
| 申请人 |
HOFFMAN LA-ROCHE, INC.;THE PENNSYLVANIA STATE UNIVERSITY |
发明人 |
GUBLER, ULRICH A.;LOMEDICO, PETER T.;MIZEL, STEVEN B. |
| 分类号 |
C12N1/19;A61K35/12;A61K35/74;A61K38/00;A61K38/16;A61P3/00;A61P37/04;A61P43/00;C07H21/04;C07K14/52;C07K14/54;C07K14/545;C07K17/10;C12N1/21;C12N5/00;C12N5/10;C12N15/00;C12N15/09;C12N15/73;C12P21/02;C12R1/19;C12R1/865;C12R1/91;(IPC1-7):A61K38/20 |
主分类号 |
C12N1/19 |
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