发明名称 Process for producing a pharmaceutical preparation of PDGF-AB
摘要 The recombinant production of PDGF-AB in mammalian cells is disclosed by means of a bicistronic vector system in which an IRES sequence is located between the first and second cistrons and in which the B chain coding gene is located in the first cistron. The disclosed expression unit allows the equilmolar expression of the A and B polypeptide chains.
申请公布号 US5935819(A) 申请公布日期 1999.08.10
申请号 US19970778275 申请日期 1997.01.02
申请人 EICHNER, WOLFRAM;ACHTERBERG, VOLKER;DORSCHNER, ALBRECHT;MEYER-INGOLD, WOLFGANG;MIELKE, HEIKO;DIRKS, WILHEM;WIRTH, MANFRED;HAUSER, HANSJOERG 发明人 EICHNER, WOLFRAM;ACHTERBERG, VOLKER;DORSCHNER, ALBRECHT;MEYER-INGOLD, WOLFGANG;MIELKE, HEIKO;DIRKS, WILHEM;WIRTH, MANFRED;HAUSER, HANSJOERG
分类号 C12N15/09;A61K38/00;A61K38/22;A61P43/00;C07H21/04;C07K14/49;C07K19/00;C12N1/21;C12N5/00;C12N5/10;C12N15/12;C12N15/16;C12N15/18;C12N15/85;C12P21/02;C12R1/91;(IPC1-7):C12N15/16;C12N15/06;C12N15/63;A61K38/18 主分类号 C12N15/09
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