发明名称 FLUORESCENT DYE
摘要 Fluorescent dyes possess reactive linkers for conjugating to nucleic acids, carbohydrates and peptides. The conjugates fluoresce in the visible and UV spectrum and have an excellent solvochromatic response as compared to other fluorescence or chromatic labels. The conjugates are stable but also have medium sensitive. The fluorescent dyes have little triplet state formation and are not photoreactive, making them an excellent substance for biological investigations. Uses for the dyes include protein labeling, DNA labeling, single molecule spectroscopy and fluorescence. A synthesis of the dyes is disclosed. Methods of use include the detection of carbohydrate-protein interactions.
申请公布号 WO9938919(A1) 申请公布日期 1999.08.05
申请号 WO1999EP00598 申请日期 1999.01.29
申请人 NOVARTIS AG;NOVARTIS-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H.;THE SCRIPPS RESEARCH INSTITUTE 发明人 LACLAIR, JAMES, J.
分类号 C09B23/14;C12Q1/34;G01N33/58;(IPC1-7):C09B23/14;C09B57/00;G01N33/50 主分类号 C09B23/14
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