Compositions comprising isolated Helicobacter pylori CagI polynucleotides and method of preparation thereof

摘要

Helicobacter pylori is known to cause or be a cofactor in type B gastritis, peptic ulcers, and gastric tumors. In both developed and developing countries, a high percentage of people are infected with this bacterium. The present invention relates generally to a certain H. pylori region located 5' to the CagA gene locus, to proteins encoded thereby, and to the use of these genes and proteins for diagnostic and vaccine applications.