发明名称 |
Anti-inflammatory eye drop |
摘要 |
PCT No. PCT/JP95/02680 Sec. 371 Date Jul. 21, 1997 Sec. 102(e) Date Jul. 21, 1997 PCT Filed Dec. 26, 1995 PCT Pub. No. WO96/22088 PCT Pub. Date Jul. 25, 1996An anti-inflammatory eye drop comprises (a) 0.05 to 0.7 weight/volume % of diclofenac sodium; (b) 1 to 10 weight/volume % of gamma -cyclodextrin; (c) 1 to 20 weight/volume % of polyvinyl pyrrolidone; and (d) 0.002 to 0.01 weight/volume % of benzethonium chloride or 0.002 to 0.005 weight/volume % of benzalkonium chloride, and has a pH value ranging from 7.0 to 8.5. The anti-inflammatory eye drop may comprise diclofenac sodium in a wide range of concentration, is stable over a long time period and shows only a low degree of ocular irritation.
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申请公布号 |
US5929115(A) |
申请公布日期 |
1999.07.27 |
申请号 |
US19970875101 |
申请日期 |
1997.07.21 |
申请人 |
WAKAMOTO PHARMACEUTICAL CO., LTD. |
发明人 |
TAKEUCHI, MASANOBU;MARUYAMA, HIROKI;SUZUKI, HIROE;OGUMA, TOURU;MAEDA, MAKOTO |
分类号 |
A61F9/00;A61K9/00;A61K31/196;A61K47/40;(IPC1-7):A61K31/195 |
主分类号 |
A61F9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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