| 发明名称 |
POLYPEPTIDES, DNA CODING THEREFOR, FORMULATIONS THEREOF, AND THEIR USE IN INHIBITING FACTOR XII ACTIVATION |
| 摘要 |
A polypeptide, derivable from a Haementeria leech, which polypeptide is suitable for inhibiting C1 esterase and/or factor XII activation is disclosed, together with a nucleic acid sequence encoding the polypeptide. The polypeptide may be used as a pharmaceutical formulation or in gene therapy to treat or prevent cardiovascular, inflammatory or auto-immune disorders.
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| 申请公布号 |
CA2318358(A1) |
申请公布日期 |
1999.07.22 |
| 申请号 |
CA19992318358 |
申请日期 |
1999.01.15 |
| 申请人 |
BIO-DISCOVERY LIMITED |
发明人 |
SEALE, LISA;FINNEY, SARAH |
| 分类号 |
C12N15/09;A61K35/62;A61K38/00;A61K38/55;A61K48/00;A61P7/02;A61P9/00;A61P9/10;A61P29/00;A61P37/02;A61P43/00;C07K14/81;C07K14/815;C12N1/21;C12N15/12;C12P21/02;(IPC1-7):C12N15/12;C12N15/70;A61K38/58;A61P7/00 |
主分类号 |
C12N15/09 |
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