发明名称 |
Phosphatase inhibitors and methods of use thereof |
摘要 |
The present invention is directed to compounds having the formula: The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
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申请公布号 |
US5925660(A) |
申请公布日期 |
1999.07.20 |
申请号 |
US19970917016 |
申请日期 |
1997.08.22 |
申请人 |
UNIVERSITY OF PITTSBURGH |
发明人 |
LAZO, JOHN S.;RICE, ROBERT L.;CUNNINGHAM, APRIL;WIPF, PETER |
分类号 |
A61K31/421;A61P35/00;A61P43/00;C07D263/34;(IPC1-7):A61K31/42;A61K31/47;A61K31/445;A61K31/44;A61K31/495 |
主分类号 |
A61K31/421 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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