发明名称 Phosphatase inhibitors and methods of use thereof
摘要 The present invention is directed to compounds having the formula: The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
申请公布号 US5925660(A) 申请公布日期 1999.07.20
申请号 US19970917016 申请日期 1997.08.22
申请人 UNIVERSITY OF PITTSBURGH 发明人 LAZO, JOHN S.;RICE, ROBERT L.;CUNNINGHAM, APRIL;WIPF, PETER
分类号 A61K31/421;A61P35/00;A61P43/00;C07D263/34;(IPC1-7):A61K31/42;A61K31/47;A61K31/445;A61K31/44;A61K31/495 主分类号 A61K31/421
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