发明名称 |
Identifying sequence differences in nucleic acid populations |
摘要 |
Methods of identifying sequence differences between or among nucleic acid populations are described. Nucleic acid strands from different populations are hybridized with one another so that mismatch-containing duplexes are formed. Mismatch-containing duplexes are cleaved in a mismatch-dependent fashion and cleavage products are isolated and used to identify the genetic sequences that differ in the nucleic acid populations.
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申请公布号 |
US5922535(A) |
申请公布日期 |
1999.07.13 |
申请号 |
US19950553185 |
申请日期 |
1995.11.07 |
申请人 |
HUO, LI |
发明人 |
HUO, LI |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;C07H21/02;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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