| 发明名称 |
Pharmaceutical composition for antagonizing ccr5 comprising anilide derivative |
| 摘要 |
This invention is to provide a pharmaceutical composition for antagonizing CCR5 which comprises a compound of the formula:wherein R1 is an optionally substituted 5- to 6-membered ring; W is a divalent group of the formula:wherein the ring A is an optionally substituted 5- to 6-membered aromatic ring, X is an optionally substituted C, N or O atom, and the ring B is an optionally substituted 5- to 7-membered ring; Z is a chemical bond or a divalent group; R2 is (1) an optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, etc., or a salt thereof. |
| 申请公布号 |
AU1683199(A) |
申请公布日期 |
1999.07.12 |
| 申请号 |
AU19990016831 |
申请日期 |
1998.12.17 |
| 申请人 |
TAKEDA CHEMICAL INDUSTRIES LTD. |
发明人 |
OSAMU NISHIMURA;MASANORI BABA;HIDEKAZU SAWADA;NAOYUKI KANZAKI;KEN-ICHI KUROSHIMA;MITSURU SHIRAISHI;YOSHIO ARAMAKI |
| 分类号 |
C07D295/12;A61K31/00;A61K31/165;A61K31/167;A61K31/335;A61K31/34;A61K31/341;A61K31/35;A61K31/351;A61K31/357;A61K31/36;A61K31/38;A61K31/381;A61K31/40;A61K31/415;A61K31/425;A61K31/426;A61K31/435;A61K31/439;A61K31/44;A61K31/443;A61K31/4433;A61K31/445;A61K31/4453;A61K31/452;A61K31/4523;A61K31/47;A61K31/495;A61K31/535;A61K31/5375;A61K31/5377;A61K31/55;A61K31/66;A61K31/665;A61K31/67;A61K45/06;A61P31/00;A61P31/12;A61P31/18;A61P37/00;A61P37/04;A61P43/00;C07C233/62;C07D211/62;C07D213/20;C07D213/56;C07D213/74;C07D213/89;C07D233/60;C07D277/22;C07D307/52;C07D309/14;C07D313/08;C07D317/58;C07D319/16;C07D333/54;C07D337/08;C07D405/12;C07D405/14;C07D407/12;C07D407/14;C07D409/12;C07D453/02;C07F9/44 |
主分类号 |
C07D295/12 |
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