Methods and compositions are disclosed for enhancing magnetic resonance imaging and spectroscopy which utilize derivatives of the even-numbered carbon clusters, known as "fullerenes." Perfluorinated carbon clusters of the formula CnFm, wherein n is in the range from 30-100 and m</=n, may be used for fluorine-19 imaging. Incorporating paramagnetic metal species into the carbon cluster cage improves fluorine and proton imaging.
申请公布号
DE69229348(D1)
申请公布日期
1999.07.08
申请号
DE1992629348
申请日期
1992.07.30
申请人
MALLINCKRODT MEDICAL, INC., ST. LOUIS, MO., US
发明人
NEUMANN, WILLIAM L., GROVER, MO 63040, US;CACHERIS, WILLIAM P., FLORISSANT, MO 63043, US
