This invention provides a method for prolonging the preservation of human blood platelets at reduced temperatures. The method uses an inhibitor system that enables blood platelets to maintain their discoid shape and retain their functional integrity during storage. This is accomplished by interrupting normal platelet function during storage, so as to help keep platelets from activating and losing their shape. Before using the platelets in a transfusion, they are returned to their normal functional level by washing the inhibitor system away from the platelets.
申请公布号
DE69509913(D1)
申请公布日期
1999.07.01
申请号
DE1995609913
申请日期
1995.10.19
申请人
LIFECELL CORP., THE WOODLANDS, TEX., US
发明人
LIVESEY, STEPHEN, A., VIC 3095, AU;CONNOR, JEROME, THE WOODLANDS, TX 77381, US;CURRIE, LAURA, M., HOUSTON, TX 77090, US