| 发明名称 |
NOVEL BENZENESULFONYLIMINE DERIVATIVES AS INHIBITORS OF IL-1 ACTION |
| 摘要 |
<p>PCT No. PCT/US94/12658 Sec. 371 Date Aug. 6, 1996 Sec. 102(e) Date Aug. 6, 1996 PCT Filed Nov. 3, 1994 PCT Pub. No. WO95/14669 PCT Pub. Date Jun. 1, 1995The present invention relates to novel benzenesulfonylimine derivatives and their use as inhibitors of Interleukin-1 (IL-1) action. Such inhibitors are useful in the treatment of various disease states as disclosed herein including: rheumatoid arthritis, multiple sclerosis, diabetes mellitus, atherosclerosis, septic shock and pulmonary fibrosis.</p> |
| 申请公布号 |
GR3029827(T3) |
申请公布日期 |
1999.06.30 |
| 申请号 |
GR19990400918T |
申请日期 |
1999.03.30 |
| 申请人 |
MERRELL PHARMACEUTICALS INC. |
发明人 |
HARRISON, BOYD, L.;KU, GEORGE;MEIKRANTZ, SCOTT, B.;DALTON, CHRISTOPHER, R.;STEMERICK, DAVID, M. |
| 分类号 |
C07D335/06;A61K31/35;A61K31/352;A61K31/38;A61K31/382;A61K31/47;A61P3/08;A61P3/10;A61P9/10;A61P29/00;A61P37/00;A61P43/00;C07D215/42;C07D311/68;(IPC1-7):C07D215/42 |
主分类号 |
C07D335/06 |
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