发明名称 Pretargeting methods and compounds
摘要 Methods, compounds, compositions and kits that relate to pretargeted delivery of diagnostic and therapeutic agents are disclosed. In particular, methods for radiometal labeling of biotin and for improved radiohalogenation of biotin, as well as related compounds, are described. Also, clearing agents, anti-ligand-targeting moiety conjugates, target cell retention enhancing moieties and additional methods are discussed.
申请公布号 US5914312(A) 申请公布日期 1999.06.22
申请号 US19940297429 申请日期 1994.08.26
申请人 NEORX CORPORATION 发明人 AXWORTHY, DONALD B.;FRITZBERG, ALAN R.;SANDERSON, JAMES A.
分类号 A61K47/48;A61K51/04;A61K51/12;(IPC1-7):C07K14/435;C07K14/47;C07D257/02 主分类号 A61K47/48
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