摘要 |
<p>Novel erythromycin derivatives represented by general formula (I) and drugs containing these derivatives as the active ingredient and being useful in treating atypical acid-fast bacterium infection, wherein R1 represents hydrogen or lower alkyl; R2 represents alkyl, cycloalkyl, aryl, aralkyl, -X-R4, etc. (wherein X represents oxygen or amino; and R4 represents alkyl or aryl); and R3 represents alkyl, cycloalkyl, alkenyl or -(CH¿2?)n-Y-R?5¿ (wherein Y represents methylene, oxygen, sulfur, sulfinyl, carbonyl, etc.; R5 represents aryl; and n is an integer of 1 to 5).</p> |