摘要 |
An apparatus (10) and method provide automated collection and transfer of particles from a liquid suspension to a glass slide for visual examination. A solution which contains particles, for example cells, is drawn through a filter element [68 (FIG. 2)] so that particles too large to pass through the filter element collect against a first surface of the filter element. A transfer fluid, such as alcohol, is applied from a second surface of the filter element to the first surface, to transfer cells from the filter element to a glass slide positioned adjacent the filter element. An alternative transfer mechanism applies a selected pneumatic signal to the filter element for transferring collected cells to the viewing slide. The apparatus includes a device [66 (FIG. 2)] for dispersing the liquid suspension of particles prior to the collection process and particles collect against the filter element with a spatial distribution advantageous for visual examination. The transfer operation maintains this spatial distribution. The cell-dispersing device and the filter element are on a common structure (22), for unitary movement, and which is readily disposable and replaceable for each sample of particles. <IMAGE> |
申请人 |
CYTYC CORP., MARLBORO, MASS., US |
发明人 |
LAPIDUS, STANLEY N., BEDFORD, NEW HAMPSHIRE 03102, US;POLK, LEWIS T., JR., BEDFORD, MASSACHUSETTS 01730, US;FARBER, FREDERIC L., CHESTNUT HILL, MASSACHUSETTS 02167, US;BARLAS, MORGAN J., MALDEN, MASSACHUSETTS 02143, US;HURLEY, ANNE A., CARVER, MASSACHUSETTS 02330, US |