NON-AQUEOUS POLAR APROTIC PEPTIDE FORMULATIONS

摘要

A stable non-aqueous formulation of a peptide compound comprises:- a) an LHRH-related compound; and b) at least one polar aprotic solvent selected from the group consisting of DMSO and DMF, wherein said formulation is stable at 37 DEG C for at least 3 months. The formulation is useful for treating disease, for example prostatic cancer. Also is disclosed is a method for preparing a stable non-aqueous formulation, which method comprises dissolving an LHRH-related compound in at least one polar aprotic solvent selected from the group consisting of DMSO and DMF.