发明名称 |
A METHOD FOR IN VIVO DNA DELIVERY USING A NEEDLE FREE APPARATUS |
摘要 |
The present invention relates to the use of a solution comprising a noninfectious DNA molecule able to express in a mammal, a physiologically active protein, for the manufacture of a medicament intended to be delivered mainly to the mammalian skin using a needle-free apparatus adapted to this effect. The physiologically active protein can be an antigen that is (i) specific for a microorganism able to induce an infection in a mammal or (ii) tumorassociated; in this case the medicament is for treating or preventing an infection or a tumor disorder. The protein can also be a mammalian protein able to treat a genetic defect e.g., factor XIII or IX; or a cytokine.
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申请公布号 |
CA2310029(A1) |
申请公布日期 |
1999.06.03 |
申请号 |
CA19982310029 |
申请日期 |
1998.11.20 |
申请人 |
AVENTIS PASTEUR |
发明人 |
HAENSLER, JEAN;ERDILE, LORNE |
分类号 |
A61K48/00;(IPC1-7):A61K48/00 |
主分类号 |
A61K48/00 |
代理机构 |
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地址 |
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