发明名称 INTERMEDIATES USEFUL FOR THE PREPARATION OF PENEMS
摘要 Disclosed is a compound of the formula: wherein R is -CH2CX=CH2, -CH2CH2S1(CH3)3, p-nitrobenzyl, or a conventional radical forming an ester which is hydrolyzed under physiological conditions; X is H or C1; R1 is a conventional silyl protecting group; and Z, X1 and X2 are taken together and are ; or Z, X1 and X2 are taken separately, X1 and X2 are each hydrogen, and Z is p-nitrophenyloxycarbonyl. The compound is useful for the synthesis of certain 6-(1-hydroxyethyl) 2-substituted penem antibiotics.
申请公布号 CA1340579(C) 申请公布日期 1999.06.01
申请号 CA19980617088 申请日期 1998.01.29
申请人 PFIZER INC. 发明人 O'NEIL, BRIAN THOMAS;PHILLIPS, DOUGLAS
分类号 C07F7/10;(IPC1-7):C07F7/10 主分类号 C07F7/10
代理机构 代理人
主权项
地址