SUBSTITUTED PHOSPHINIC COMPOUNDS PREPARATION AND THEIR USE AS PHARMACEUTICALS AND PHARMACEUTICAL COMPOSITIONS

摘要

A compound which is a substituted phosphinic acid of formula (I), or a salt or ester thereof, where R<1> is a monovalent aromatic or araliphatic group connected through a carbon atom thereof to the indicated carbon atom, R<2> is an unsubstituted or substituted hydrocarbyl group, R is hydrogen or an unsubstituted or substituted hydrocarbyl group, R is hydrogen, Ra or a NH-protecting group and Ra is an unsubstituted or substituted hydrocarbyl group.