| 发明名称 |
LITHIUM SALTS OF (I'R,5'R)-3'-AZA-3'-(AZIDONAPHTHALINE-1- SULFAMIDO)-1'-(6-AMINOPURINYL-9)-3'-DEOXYHEXOPIRANOZYL- 6'-DI-OR TRIPHOSPHATES AS SPESIFIC PHOTOACTIVATED IRREVERSIBLE INHIBITORS OF Na, K-ADENOSINE TRIPHOSPHATASE |
| 摘要 |
FIELD: biochemistry. SUBSTANCE: lithium salts of (1'R, 5'R)-3'-aza-3'-azidonaphthalene-1- sulfamino-1'-(6-amino-purinyl-9)-3'-deoxyhexopyranozyl-6- di-or triphosphates of general formula I: R<SP>1</SP>=N<SB>3</SB>,R<SP>2</SP>=H or R<SP>1</SP>=H and R<SP>2</SP>=N<SB>3</SB> wherein n is 2 or 3, <EMI ID=0.304 HE=66 WI=66 TI=CHI> are useful for specific inhibition of Na, K-adenonosine triphosphatase. EFFECT: improved properties of the title compounds. 4 ex, 1 tbl
|
| 申请公布号 |
RU2130943(C1) |
申请公布日期 |
1999.05.27 |
| 申请号 |
RU19970119763 |
申请日期 |
1997.11.28 |
| 申请人 |
BIOLOGICHESKIJ FAKUL'TET MGU IM.M.V.LOMONOSOVA |
发明人 |
KHROPOV JU.V.;MISHIN A.A.;SELIVERSTOV V.O.;KULAGIN S.V.;LOPINA O.D. |
| 分类号 |
C07H19/16;C07H19/20;C12N9/99;(IPC1-7):C07H19/16 |
主分类号 |
C07H19/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
