发明名称 |
Adjustable sensitivity, genetic molecular interaction systems, including protein-protein interaction systems for detection and analysis |
摘要 |
A method for detecting interactions between first and second interacting molecules at variable sensitivity. This variable sensitivity may be obtained by providing for the overexpression of either a bait hybrid protein containing a DNA binding domain (desensitization) or a prey hybrid protein containing the DNA activation domain for a reporter gene (enhanced sensitivity). The use of exogenous activators of one or the other according to the needs of a particular system is readily accomplished. |
申请公布号 |
AU1074401(A) |
申请公布日期 |
2001.05.10 |
申请号 |
AU20010010744 |
申请日期 |
2000.10.06 |
申请人 |
HYBRIGEN, INC. |
发明人 |
DAVID N. EDWARDS;ARLENE LEON;DAVID F. RANNEY |
分类号 |
C12N15/09;C12N15/10;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|