A method of coating an active material is provided. The method comprises contacting an active material with a film-forming composition comprising an aqueous dispersion of an amylose-alcohol complex, an insoluble film-forming polymer and a plasticiser at a temperature of less than 60 DEG C. The method finds particular application in the preparation of dosage forms comprising active materials that are unstable at temperatures in excess of 60 DEG C. The compositions prepared in accordance with the method can be used to deliver an active material to the colon.
申请公布号
WO9925325(A1)
申请公布日期
1999.05.27
申请号
WO1998GB03428
申请日期
1998.11.13
申请人
BTG INTERNATIONAL LIMITED;NEWTON, JOHN, MICHAEL;LEONG, CHUEI, WUEI