摘要 |
Object: to provide compounds having an inhibitory effect on the production of inflammatory cytokines. Constitution: compounds having general formula (I), pharmacologically acceptable salts thereof or derivatives of the same, wherein A: single bond, oxygen, sulfur, CO, SO, SO2, C(R9)(R10) ¢R9, R10: H, OH, halogeno, alkyl!, N(R11), C=NOR11 ¢R11: H, alkyl!; D: single bond, C(R12)(R13) ¢R12, R13: H, OH, halogeno, alkyl!; R1: optionally substituted pyridyl; R2: optionally substituted phenyl; R3: halogeno, alkyl, haloalkyl, alkoxy, haloalkoxy; R4, R5, R6, R7, R8: H, alkyl; k: 0-3; and m: 1, 2.
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