摘要 |
Phospholipid-nucleoside adducts (I) are new. Phospholipid-nucleoside adducts of formula (I) are new. R = 4-22C hydrocarbon group which is saturated or unsaturated and may be substituted by one or more halo, OH, alkoxy or CN groups, or R = -CH2-CH(B)-CH2Q or -CH(CH2Q)(CH2B); (F-ara-A) = 9- beta -D-arabinofuranosyl-2-fluoroadenyl-5'-group; n, m = 0 or 1; Q = 5-30C alkoxy or alkenyloxy which are saturated or unsaturated and which may be substituted by one or more halo, OH, alkoxy or CN groups; B has the same meaning as Q or is H, OH, halo, CN, 2,2,2-trifluoroethoxy or 2-22C acyloxy.
|
申请人 |
MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN, 13125 BERLIN, DE |
发明人 |
BRACHWITZ, HANS, DR., 10439 BERLIN, DE;WOLLNY, THOMAS, DR., 12161 BERLIN, DE;BERGMANN, JUTTA, DR., 16348 WANDLITZ, DE;LANGEN, PETER, PROF., 13125 BERLIN, DE;THOMAS, YVONNE, 13051 BERLIN, DE |