发明名称 |
PROCESS FOR THE PREPARATION OF CYCLOHEXYL-AZETIDINONES |
摘要 |
<p>PCT No. PCT/EP95/01114 Sec. 371 Date Jan. 3, 1997 Sec. 102(e) Date Jan. 3, 1997 PCT Filed Mar. 23, 1995 PCT Pub. No. WO95/26333 PCT Pub. Date Oct. 5, 19951. A process for the preparation of compounds of formula (I) wherein R1 is a hydroxyl protecting group <IMAGE> (I) which comprises reacting the azetidinone (II) with the homochiral (2S)-2- methoxycyclohexane (III) or the complex thereof formed with one molecule of stannic chloide. <IMAGE> (II) <IMAGE> (III)</p> |
申请公布号 |
EP0752984(B1) |
申请公布日期 |
1999.05.19 |
申请号 |
EP19950914304 |
申请日期 |
1995.03.23 |
申请人 |
GLAXO WELLCOME S.P.A. |
发明人 |
ROSSI, TINO;ZARANTONELLO, PAOLA;THOMAS, JOHN, RUSSEL |
分类号 |
B01J31/02;C07D205/08;C07F7/18;(IPC1-7):C07D205/08 |
主分类号 |
B01J31/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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