发明名称 OLIGONUCLEOTIDE PROBE SPECIFIC IN SPECIES TO BACTEROIDES GROUP BACTERIUM
摘要 PROBLEM TO BE SOLVED: To obtain the subject new probe comprising an oligonucleotide probe having a specific base sequence or a sequence complementary to the base sequence and useful for identification of species of bacteroides group bacterium in the intestine and analysis or the like of intestinal flora. SOLUTION: This oligonucleotide probe has a base sequence represented by formula I to formula V or the like or a base sequence which is complementary to the base sequence and each base sequence of the following formulas is specific to the following species of bacteroides (B) group bacterium and useful for specific identification or the like of bacteroides group bacterium: The sequence of formula I: Bacteroides ovatus, the sequence of formula II: Bacteroides fragilis, the sequence of formula III: Bacteroides uniformis, the sequence of formula IV: Bacteroides eggerthii, the sequence of formula V: Porphyromonas asaccharolytica. These probes are obtained by comparing 16Sr RNA gene sequence of each species of bacteroides group registered in database and designing the structure and synthesizing these sequences by DNA synthesizer.
申请公布号 JPH11127899(A) 申请公布日期 1999.05.18
申请号 JP19970297085 申请日期 1997.10.29
申请人 YAKULT BIO SCIENCE KENKYU ZAIDAN 发明人 TOOMA YUKIKO;ITO KIKUJI
分类号 C12N15/09;C12N15/00;C12Q1/68;C12R1/01 主分类号 C12N15/09
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