摘要 |
PROBLEM TO BE SOLVED: To obtain the subject new probe comprising an oligonucleotide probe having a specific base sequence or a sequence complementary to the base sequence and useful for identification of species of bacteroides group bacterium in the intestine and analysis or the like of intestinal flora. SOLUTION: This oligonucleotide probe has a base sequence represented by formula I to formula V or the like or a base sequence which is complementary to the base sequence and each base sequence of the following formulas is specific to the following species of bacteroides (B) group bacterium and useful for specific identification or the like of bacteroides group bacterium: The sequence of formula I: Bacteroides ovatus, the sequence of formula II: Bacteroides fragilis, the sequence of formula III: Bacteroides uniformis, the sequence of formula IV: Bacteroides eggerthii, the sequence of formula V: Porphyromonas asaccharolytica. These probes are obtained by comparing 16Sr RNA gene sequence of each species of bacteroides group registered in database and designing the structure and synthesizing these sequences by DNA synthesizer. |