发明名称 |
Forbedret fremgangsmåde til fremstilling af en forbindelse afledt af aspartam som er anvendelig som sødemiddel |
摘要 |
A method of preparing N-[N-(3,3-dimethylbutyl)-L- alpha -aspartyl]-L-phenylalanine 1-methyl ester of the formula <IMAGE> useful as a sweetening agent, wherein an aqueous-alcoholic solution of aspartame and 3,3-dimethylbutyraldehyde of pH 4.5-5 is treated, at room temperature, with hydrogen at a pressure less than or equal to 1 bar, in the presence of a catalyst selected from the group comprising platinum or palladium on activated carbon or in the form of platinum or palladium black, and wherein the product formed is purified by precipitation and filtration after removal of the alcohol part of the solvent under vacuum. |
申请公布号 |
DK0759031(T3) |
申请公布日期 |
1999.05.17 |
申请号 |
DK19950919484T |
申请日期 |
1995.05.05 |
申请人 |
NOFRE, CLAUDE;TINTI, JEAN-MARIE |
发明人 |
NOFRE, CLAUDE;TINTI, JEAN-MARIE |
分类号 |
A23L27/20;A23L27/30;C07K1/107;C07K1/113;C07K5/06;C07K5/072;C07K5/075 |
主分类号 |
A23L27/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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