发明名称 Morpholino-n-ethyl ester prodrugs of indole spla<sub>2</sub> inhibitors
摘要 The compound, ((3(2-amino-1,2-dioxoethyl)-1-((1,1'-biphenyl)-3-ylmethyl)-2-methyl-1H-indol-4-yl)oxy)acetic acid morpholino-ethyl ester, is disclosed together with its use as a highly bioavailable indole compound for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.
申请公布号 AU1200899(A) 申请公布日期 1999.05.17
申请号 AU19990012008 申请日期 1998.10.26
申请人 ELI LILLY AND COMPANY 发明人 MICHAEL LYLE DENNEY;JOHN MICHAEL MORIN;DANIEL JON SALL;JASON SCOTT SAWYER
分类号 A61K31/5377;A61P1/00;A61P7/00;A61P11/00;A61P11/06;A61P19/02;A61P19/06;A61P29/00;A61P43/00;C07D209/14;C07D209/42 主分类号 A61K31/5377
代理机构 代理人
主权项
地址