发明名称 COMPOSITIONS OF LIPID LOWERING AGENTS
摘要 The present invention is concerned with novel pharmaceutical compositions of lipid lowering agents which can be administered to a mammal suffering from hyperlipidemia, obesitas or atherosclerosis, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising a lipid lowering agent and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.
申请公布号 WO9922738(A1) 申请公布日期 1999.05.14
申请号 WO1998EP06998 申请日期 1998.10.27
申请人 JANSSEN PHARMACEUTICA N.V.;BAERT, LIEVEN;VERRECK, GEERT 发明人 BAERT, LIEVEN;VERRECK, GEERT
分类号 C07D405/14;A61K9/14;A61K9/20;A61K9/30;A61K9/50;A61K9/58;A61K31/495;A61K31/496;A61K31/506;A61K38/11;A61K38/22;A61K47/38;A61P3/06;A61P9/10;C07D413/14;C07D417/14;(IPC1-7):A61K31/495 主分类号 C07D405/14
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