| 发明名称 |
Certain sulfoxide and sulfone derivatives |
| 摘要 |
The present invention relates to thio derivatives that inhibit N-Acetylated alpha -Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising such derivatives, and methods of using such derivatives to inhibit NAALADase activity, to treat a glutamate abnormality and to treat a prostate disease in an animal.
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| 申请公布号 |
US5902817(A) |
申请公布日期 |
1999.05.11 |
| 申请号 |
US19970835572 |
申请日期 |
1997.04.09 |
| 申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
JACKSON, PAUL F.;TAYS, KEVIN L.;MACLIN, KEITH M.;SLUSHER, BARBARA S. |
| 分类号 |
C07D213/71;A61K31/194;A61K31/4409;A61K38/05;A61K38/06;A61P13/08;A61P35/00;C07C317/44;C07C381/10;C07F9/30;(IPC1-7):A61K31/44;A61K31/19;C07C317/06 |
主分类号 |
C07D213/71 |
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