发明名称 Preparing porous polyolefin particles, used as controlled release carriers
摘要 Preparing porous polyolefin particles comprises forming a solution of a crystallisable polyolefin, dispersing this in a non-solvent in the presence of a surfactant at above the crystallisation temperature to give a multi-phase system and cooling at 0.05-10 deg C per minute with stirring to below the crystallisation temperature to give firm particles. These are then separated and dried. Also claimed are particles formed having a porosity of 5-85%, an effective loadability, E1a /- 95%, where E1a = 100 /* [(ma/~ra)/(ma/~ra + mpo/~rpo)] / porosity (I). In (I), m = the weight of the polyolefin (po) and absorption agent (a) and ~r their respective densities. The absorption time /- 10 minutes and the degree of dispersion of the particle size 0.4.
申请公布号 NL1007333(C1) 申请公布日期 1999.04.27
申请号 NL19971007333 申请日期 1997.10.23
申请人 DSM N.V. 发明人 ROELOF FRANCISCUS GERARDUS MARIA DE VOS
分类号 A61K47/32;C08J3/14;C08J9/28;(IPC1-7):C08J9/28;A01N25/10;A61K47/30;B01J20/26;C08L23/02 主分类号 A61K47/32
代理机构 代理人
主权项
地址