| 发明名称 |
Inhibitors of prenyl-protein transferase |
| 摘要 |
The present invention is directed to compounds which inhibit prenyl-protein transferase (FTase) and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras. |
| 申请公布号 |
AU9781098(A) |
申请公布日期 |
1999.04.27 |
| 申请号 |
AU19980097810 |
申请日期 |
1998.10.01 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
S. JANE DESOLMS;ANTHONY W. SHAW;WILLIAM C. LUMMA;JOHN T. SISKO;THOMAS J. TUCKER |
| 分类号 |
A61K31/4427;A61K31/4439;A61P9/10;A61P35/00;A61P43/00;C07D401/06;C07D401/12;C07D401/14 |
主分类号 |
A61K31/4427 |
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