PROCESS FOR THE SYNTHESIS OF CHLOROPURINE INTERMEDIATES
摘要
<p>The present invention relates to a process for the preparation of a carbocyclic purine nucleoside analogue of formula (I), its salts and pharmaceutically acceptable derivatives thereof which comprises hydrolysing a compound of formula (IV) wherein P is a protecting group, in the presence of an acid, condensing the product of formula (V) formed in situ in the presence of a base with a compound of formula (VI) followed by in situ ring closure of the resulting intermediate.</p>
申请公布号
WO9919327(A1)
申请公布日期
1999.04.22
申请号
WO1998GB03080
申请日期
1998.10.14
申请人
GLAXO GROUP LIMITED;JONES, MARTIN, FRANCIS;WALLIS, CHRISTOPHER, JOHN