| 发明名称 |
METHOD FOR PREPARING SUBSTITUTED 4-PHENYL-4-CYANOCYCLOHEXANOIC ACIDS |
| 摘要 |
This invention relates to a method of preparing a compound type where at least one of R' or R'' is a carboxyl group (I) by treating a compound of formula (II) with a Group I(a) or Group II(a) metal halide, with an aprotic dipolar amide-based solvent and water.
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| 申请公布号 |
WO9918793(A1) |
申请公布日期 |
1999.04.22 |
| 申请号 |
WO1998US21061 |
申请日期 |
1998.10.07 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION;WEBB, KEVIN;MENDELSON, WILFORD;CHEN, JIANHAO |
发明人 |
WEBB, KEVIN;MENDELSON, WILFORD;CHEN, JIANHAO |
| 分类号 |
A61K31/275;A61P11/06;A61P43/00;C07C41/22;C07C41/26;C07C43/253;C07C45/71;C07C47/575;C07C253/30;C07C255/46;C07D303/48;(IPC1-7):A01N43/38;A01N43/20;A01N43/24;A01N37/34 |
主分类号 |
A61K31/275 |
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