摘要 |
FIELD: medicine. SUBSTANCE: invention relates to treatment of mammals with bacterial infection. After eating an effective dose of azithromycin as an oral drug is administrated to mammals. Solubility of azithromycin is 90% for 30 min when amount of drug containing 200 mg azithromycin is tested by method VSP-711 in an advice VSP-2 for dissolving under the rigid conditions that correspond the following indices: 90 ml sodium-phosphate buffer, pH 6.0, at 37 C using blade mixer working at 100 rev/min, and/or value AIS pich/AIS gol is at least 0.80 and at lower 90% limit of reliability, at least 0.75. Medicinal form proposed for treatment does not exhibit negative alimentary effect. EFFECT: improved method of treatment. 28 cl, 15 tbl, 14 ex
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