发明名称 METHOD OF TREATMENT OF PATIENTS WITH BACTERIAL INFECTION
摘要 FIELD: medicine. SUBSTANCE: invention relates to treatment of mammals with bacterial infection. After eating an effective dose of azithromycin as an oral drug is administrated to mammals. Solubility of azithromycin is 90% for 30 min when amount of drug containing 200 mg azithromycin is tested by method VSP-711 in an advice VSP-2 for dissolving under the rigid conditions that correspond the following indices: 90 ml sodium-phosphate buffer, pH 6.0, at 37 C using blade mixer working at 100 rev/min, and/or value AIS pich/AIS gol is at least 0.80 and at lower 90% limit of reliability, at least 0.75. Medicinal form proposed for treatment does not exhibit negative alimentary effect. EFFECT: improved method of treatment. 28 cl, 15 tbl, 14 ex
申请公布号 RU2128998(C1) 申请公布日期 1999.04.20
申请号 RU19950106639 申请日期 1995.04.28
申请人 PFAJZER INK. 发明人 VILL'JAM DZH.KURATOLO;DZHORDZH KH.FOULDZ;KHAJLER L.FRIDMAN
分类号 C07H17/00;A61K9/00;A61K9/10;A61K9/14;A61K9/20;A61K31/70;A61K31/7042;A61K31/7048;A61K31/7052;A61K47/02;A61P31/00;A61P31/04;C07H17/08;(IPC1-7):A61K31/73 主分类号 C07H17/00
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