发明名称 USE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREPARATION OF DRUGS TO INCREASE THE SURVIVAL RATE OF RENAL TRANSPLANT PATIENTS
摘要 The present invention relates to the use, for the preparation of drugs to increase the survival rate of transplant patients, including renal and heart transplant patients, of a therapeutically effective amount of an angiotensin II receptor antagonist compound, such as the class of substituted imidazoles represented by formula (I) and in particular by losartan potassium, 2-butyl-4-chloro-1-[(2'-tetrazol-5-yl)biphenyl-4-il]methyl]-5-(hydroxymethyl)imidazole potassium salt.
申请公布号 WO9916437(A1) 申请公布日期 1999.04.08
申请号 WO1998IT00259 申请日期 1998.09.30
申请人 MERCK SHARP DOHME (ITALIA) S.P.A.;REMUZZI, GIUSEPPE 发明人 REMUZZI, GIUSEPPE
分类号 C07D233/64;A61K31/4164;A61K31/4174;A61K31/4178;A61P9/12;A61P13/12;C07D233/68;C07D403/10;(IPC1-7):A61K31/415 主分类号 C07D233/64
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