发明名称 |
Chinasäurederivate und Verfahren zur Herstellung von Chinasäurederivaten |
摘要 |
<p>1- or 5-O-Mono- and 3,4-O-disubstituted quinic acid derivatives are prepared by reacting a derivative of a hydroxycinnamic acid, in which the hydroxyl group(s) is(are) protected, with a quinic acid derivative so as to form an ester and the protective groups are then cleaved under controlled acidity and temperature conditions. These controlled conditions make it possible to achieve a regiospecificity in the esterification and to avoid any degradation or isomerisation. The process makes possible the preparation of new quinides with a good yield.</p> |
申请公布号 |
DE69228541(D1) |
申请公布日期 |
1999.04.08 |
申请号 |
DE1992628541 |
申请日期 |
1992.08.03 |
申请人 |
SOCIETE DES PRODUITS NESTLE S.A., VEVEY, CH |
发明人 |
HUYNH-BA, TUONG, CH-1009 PULLY, CH |
分类号 |
A61K31/34;A61P7/02;A61P9/06;C07C67/29;C07D307/00;(IPC1-7):C07D307/00 |
主分类号 |
A61K31/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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