发明名称 |
Allergenic proteins and peptides from dog dander and use therefor |
摘要 |
Isolated nucleic acids encoding allergens of Canis familiaris, Can f I or Can f II, are disclosed. A cDNA encoding a peptide having a Can f I activity and a predicted molecular weight of about 19,200 daltons is also described. A cDNA encoding a peptide having Can f II activity and a predicted molecular weight of about 18,200 daltons is also disclosed. The nucleic acids can be used as probes to detect the presence of Can f I or Can f II nucleic acid in a sample or for the recombinant production of petides having a Can f I or Can f II activity. Peptides having a Can f I or Can f II activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to dog dander.
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申请公布号 |
US5891716(A) |
申请公布日期 |
1999.04.06 |
申请号 |
US19950466793 |
申请日期 |
1995.06.06 |
申请人 |
IMMULOGIC PHARMACEUTICAL CORPORATION |
发明人 |
MORGENSTERN, JAY P.;KONIECZNY, ANDRZEJ;BIZINKAUSKAS, CHRISTINE B.;BRAUER, ANDREW W. |
分类号 |
G01N33/53;A61K38/00;A61K39/35;A61K39/395;A61P37/08;C07K14/47;C12N1/21;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12R1/19;(IPC1-7):C12N1/21;C12N5/10;C12N15/63 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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