发明名称 |
INHIBITION OF PSYCHOSTIMULANT-INDUCED AND NICOTINE-INDUCED CRAVING |
摘要 |
The invention provides methods for inhibiting psychostimulant-induced or nicotine-induced craving of additional psychostimulants (e.g., cocaine or amphetamine) or nicotine. In these methods, D1-like antagonists or D1-like agonists are administered to a patient dependent on psychostimulant drugs or nicotine and therefore susceptible to, or suffering from, such a craving. Also disclosed is an animal model system useful for measuring the ability of test compounds to inhibit psychostimulant-induced or nicotine-induced cravings in humans. |
申请公布号 |
WO9915161(A2) |
申请公布日期 |
1999.04.01 |
申请号 |
WO1998US19945 |
申请日期 |
1998.09.24 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
BREITER, HANS, C.;ROSEN, BRUCE, R. |
分类号 |
A61K31/00;A61K31/438;A61K31/4515;A61K31/473;A61K31/4741;A61K31/4743;A61K31/4745;A61K31/48;A61K31/496;A61K31/5415;A61K31/55 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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