| 摘要 |
<p>Provided is a process for the preparation of compounds of formula (II), or a protected derivative thereof, wherein each of B1, B2, B3 and B4 independently represent the skeleton of an alpha -amino acid, D1, D2 and D3 each independently represent carbonyl or methylene, with the proviso that only one of the groups selected from D1, D2, and D3 can be methylene, and T1, T2 and T3, which are optionally present, each independently represent hydrogen or an amino acid substituent or an activating group, an amine protecting group or a linker group, which process comprises cyclising a compound of formula (III) or a protected derivative thereof, wherein P is hydrogen or carboxyl protecting group or a linker group.</p> |
