METHOD OF SYNTHESIS OF 4-METHOXY-10-(1-HYDROXYETHYL)-11-OXO- -1-AZATRICYCLO-[7.2.0.0 ]-UNDECA-2-ENE CARBOXYLIC ACID OR ITS SALTS, 4-TERTIARY-BUTYLBENZYL-(4S, 8S, 9R, 10S, 12R)-4-METHOXY-10- -(1-HYDROXYETHYL)-11-OXO-1-AZATRICYCLO-[7.2.0.0 ]-UNDECA-2-ENE-2 CARBOXYLATE

摘要

FIELD: organic chemistry. SUBSTANCE: invention relates to a method of synthesis of an antibacterial compound of the formula (I) <EMI ID=0.637 HE=33 WI=48 TI=CHI> or its salt that involves hydrogenolysis of a new compound of the formula (II) <EMI ID=0.638 HE=36 WI=78 TI=CHI> and if necessary an isolation of synthesized carboxylic acid as its salt. Invention proposes also a compound of the formula (II) used as an intermediate substance for synthesis of a compound of the formula (I). The use of compound of the formula (II) simplifies purification stage if it is necessary before the end synthesis stage carrying out. EFFECT: improved and simplified method. 9 cl, 6 ex