| 摘要 |
<p>The present invention concerns the compounds of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein R1 is hydrogen, optionally substituted C¿1-6?alkyl, aryl; R?2¿ is each independently a halogen, hydroxy, C¿1-6?alkyl, C1-6alkyloxy or nitro; n is 0, 1, 2 ou 3; Alk is C1-6alkanediyl; D is optionally substituted saturated or unsaturated nitrogen containing heterocycle; and aryl is optionally substituted phenyl; having a great therapeutic breadth. It further relates to their use as a medecine, their preparation as well as compositions containing them.</p> |
