发明名称 |
Neovascularization promoters |
摘要 |
An angiogenesis promoter containing a compound of the following formula (I) <CHEM> wherein R<1> is acyl, R<2> is alkyl, R<3> and R<4> are the same or different and each is hydrogen atom or hydroxy protecting group and R<5> is alkyl, as an active ingredient. This compound itself not only has an angiogenesis promoting effect but also potentiates the angiogenic effect by a drug (e.g., b-FGF) having such effect. Therefore, it can express the angiogenesis promoting effect more effectively in the ischemic tissues and the site under different disease state, where b-FGF has locally increased. |
申请公布号 |
AU8749998(A) |
申请公布日期 |
1999.03.16 |
申请号 |
AU19980087499 |
申请日期 |
1998.08.24 |
申请人 |
YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD.;SEIKAGAKU CORPORATION |
发明人 |
YASUHIRO EGI;YOSHIJI KUBO;SATORU INOUE;HIDEAKI KIDO;MASAKUNI NISHIKAWA;KAZUTAKA HAYASHI |
分类号 |
A61K31/557;A61K31/5575;A61K38/18;A61K45/06 |
主分类号 |
A61K31/557 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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