发明名称 |
Relating to the detection of viruses |
摘要 |
The present invention relates to polypeptides from clinical isolates of cytomegalovirus encoded by the gB coding region which include at least one amino acid variation which is a substitution, insertion or deletion wherein the polypeptides otherwise retain the character of cytomegalovirus. The amino acid variations include changes to neutralizing epitopes.
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申请公布号 |
US5883225(A) |
申请公布日期 |
1999.03.16 |
申请号 |
US19950468042 |
申请日期 |
1995.06.06 |
申请人 |
ROYAL FREE HOSPITAL SCHOOL OF MEDICINE |
发明人 |
GRUNDY, JANE;EMERY, VINCENT;GRIFFITHS, PAUL |
分类号 |
A61K39/00;A61K38/00;A61K39/245;A61K39/395;A61K39/42;A61P31/12;C07K14/00;C07K14/045;C07K16/00;C07K19/00;C12N1/21;C12N15/09;C12N15/38;C12P21/02;C12P21/08;C12Q1/68;C12R1/19;C12R1/92;G01N33/53;G01N33/569;(IPC1-7):C07K14/045 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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