发明名称 |
Method for screening for alzheimer's disease |
摘要 |
Method for screening for risk of Alzheimer's disease involve assaying for a guanine to thymine substitution at position 1924 of the gene encoding the human amyloid precursor protein. Also described are transgenic mammals harboring an expressable gene sequence encoding human amyloid precursor protein having a phenyanine for valine amino acid substitution in the transmembrane domain of the amyloid precursor protein.
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申请公布号 |
US5879883(A) |
申请公布日期 |
1999.03.09 |
申请号 |
US19950434018 |
申请日期 |
1995.05.03 |
申请人 |
INDIANA UNIVERSITY FOUNDATION |
发明人 |
BENSON, MERRILL D.;MURRELL, JILL;FARLOW, MARTIN;GHETTI, BERNARDINO |
分类号 |
C07K14/47;C12N15/12;C12N15/85;C12Q1/68;(IPC1-7):C12Q1/68;C12N15/11;C07H21/04 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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