COMBINED PREPARATIONS FOR TREATING UPPER GASTROINTESTINAL TRACT DISTRESS

摘要

The invention concerns multilayer combined preparations for oral administration to be used for disorders of the upper gastrointestinal tract, such as heartburn, indigestion or H. pylori infections. The preferred form is a tablet which releases a bismuth compound in the stomach and a proton pump inhibiting compound into the intestine. This is achieved by making an enteric coated core containing the proton pump inhibitor with an outer layer containing the bismuth compound.